Retinyl acetate-d4
Based on 1 Customer Validation
Retinyl acetate-d4 is the deuterium labeled Retinyl acetate. Retinyl acetate is a synthetic acetate ester form derived from retinol and has potential antineoplastic and chemo preventive activities.
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- Pureza: 99.4%
- No. CAS: 118139-40-5
- Fòrmula: C22H28D4O2
- Peso molecular:332.51
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Actividad biológica
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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No. CAS 118139-40-5
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Unlabeled Cas 127-47-9
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Appearance Solid
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Peso molecular 332.51
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Fòrmula C22H28D4O2
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Color White to light yellow
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SMILES
CC(OC/C=C(C)/C=C/C([2H])=C(C([2H])([2H])[2H])/C=C/C1=C(C)CCCC1(C)C)=O
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Synonyms
Retinol acetate-d4; Vitamin A acetate-d4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (264 KB)
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SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Korean - KR (418 KB)
- Portuguese - PT (418 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Moon, Richard C, et al. Retinyl acetate inhibits mammary carcinogenesis induced by N-methyl-N-nitrosourea. Nature. 1977 Jun 16;267(5612):620-1. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)