10 Results for "

paraoxonase

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "paraoxonase" in MCE Product Catalog:

Referencia número: HY-B0815S
No. CAS: 285138-81-0
Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
Referencia número: HY-W017445
No. CAS: 2688-48-4
Target:  

Fungal

Homogentisic acid lactone (Compound 1) is a fungal metabolite with fungicidal activity, which is found in the fungus WF5. Homogentisic acid lactone is active against the plant pathogenic fungus F. graminearum. Homogentisic acid lactone can be used as a substrate in the determination of serum paraoxonase/arylesterase 1 (PON1) activity .
Referencia número: HY-130220
No. CAS: 81517-87-5
Target:  

Drug Isomer

Áreas de investigación:  

Inflammation/Immunology

(±)5-HETE lactone is the racemate of 5-HETE lactone. 5-HETE lactone is a metabolite generated by a series of enzymatic reactions of arachidonic acid, and is also a substrate of paraoxonase-1 (PON1). 5-HETE lactone can be used in the study of B cell activation .
Referencia número: HY-P88420
Synonyms: lactonase 3; paraoxanase-3; paraoxonase 3; serum paraoxonase

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

Referencia número: HY-P88420A
Synonyms: lactonase 3; paraoxanase-3; paraoxonase 3; serum paraoxonase

Host:  

Mouse

Application:  

IHC-P

Reactivity:  

Human

Referencia número: HY-P81943
Synonyms: A esterase 2; paraoxonase 2; PON2

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

Referencia número: HY-P81943A
Synonyms: A esterase 2; paraoxonase 2; PON2

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

Referencia número: HY-P74623
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Serum paraoxonase/lactonase 3; PON3
Species:  
Source:  
Referencia número: HY-P81921
Synonyms: A esterase 1; Arylesterase 1; ESA; MVCD5; paraoxonase 1; PON1

Host:  

Rabbit

Application:  

WB, IHC-P, IP

Reactivity:  

Human

Referencia número: HY-182372
No. CAS: 1638153-78-2
Target:  

Epoxide Hydrolase

Áreas de investigación:  

Neurological Disease

SH-11037 is a potent inhibitor of soluble epoxide hydrolase (sEH) and docks to the substrate binding cleft in the sEH hydrolase domain. SH-11037 dose-dependently suppresses angiogenesis in the choroidal sprouting assay ex vivo and inhibited ocular developmental angiogenesis in zebrafish larvae. SH-11037 reduces choroidal neovascularisation lesion volume in the laser-induced CNV mouse model. SH-11037 synergises with anti-VEGF treatments in vitro and in vivo. SH-11037 induces G2/M phase blockade and retains retinal endothelial cell viability at active concentrations without overt toxicity. SH-11037 can be used for the research of retinal neovascularization and ocular neovascularization .