PON1 Antibody (YA1666)
(Synonyms: A esterase 1; Arylesterase 1; ESA; MVCD5; Paraoxonase 1; PON1)PON1 Antibody (YA1666) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PON1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IP
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Reactivity :
Human
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50 |
Product Details
PON1 Antibody (YA1666) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PON1.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 40 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 40 kDa
A synthesized peptide derived from human PON1 aa50-100/355.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. Capable of hydrolyzing a broad spectrum of organophosphate substrates and lactones, and a number of aromatic carboxylic acid esters. Mediates an enzymatic protection of low density lipoproteins against oxidative modification and the consequent series of events leading to atheroma formation
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Subcellular Localization
Secreted, extracellular space
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Expression
Tissue_specificity:In plasma, it is associated with high-density lipoprotein (HDL) (at the protein level) . It is expressed in the liver, but not in the heart, brain, placenta, lungs, skeletal muscle, kidneys, or pancreas. -
Subunit
Homodimer. Heterooligomer with phosphate-binding protein (HPBP). Interacts with CLU
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SwissProt ID
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Synonyms
A esterase 1; Arylesterase 1; ESA; MVCD5; Paraoxonase 1; PON1
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Research Field
Neuroscience
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