TRAF6 peptide
TRAF6 peptide is a specific TRAF6-p62 inhibitor. TRAF6 peptide potently abrogates NGF-dependent TrkA ubiquitination. TRAF6 peptide has good research potential in neurological diseases such as alzheimer's disease (AD), parkinson's, ALS, head trauma, epilepsy and stroke.
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- No. CAS: 852805-92-6
- Fòrmula: C145H238N34O44
- Peso molecular:3161.64
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
TRAF6 peptide (150 µM; 5 h) blocks the interaction of p62 with TRAF6 in PC12 cells[1].
TRAF6 peptide eliminates TRAF6 and UbcH7 from interacting with TrkA and can ffectively abolish NGF-dependent ubiquitination of TrkA in vitro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:PC12 cells
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Concentration:150 µM
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Incubation Time:5 h
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Result:Inhibited the interaction of p62 with TRAF6 by immunoprecipitating TRA F6.
Chemical Information
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No. CAS 852805-92-6
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Peso molecular 3161.64
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Fòrmula C145H238N34O44
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Sequence Shortening
AAVALLPAVLLALLAPESASGPSEDPSVNFLK
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)