SEW-05929
SEW-05929 is an inhibitor of E. coli SecA ATPase (N68SecA). SEW-05929 is applicable to research related to SecA ATPase in bacterial protein translocation and bacterial infections.
For research use only. We do not sell to patients.
- CAS No.: 260392-25-4
- Formula: C28H19ClFN3O2S2
- Molecular Weight:548.05
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SEW-05929 (100 μM; 20 min) competitively inhibits the unregulated E. coli N68SecA ATPase, with a Ki of 18 μM and an IC50 of approximately 30 μM[1].
SEW-05929 binds to the ATP-binding site of SecA, forms hydrogen bonds with Lys108, Glu210 and Arg509, and engages in hydrophobic interactions with Thr104, Gly105, Gly107, Gly392, Gly510 and Thr511[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 260392-25-4
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Molecular Weight 548.05
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Formula C28H19ClFN3O2S2
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SMILES
O=C(C1=C(C)ON=C1C2=C(Cl)C=CC=C2F)NC3=CC=C(SC4=CC=CC=C4)N=C3SC5=CC=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SEW-05929 Related Classifications
HY-129606 Related Classifications
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