2G-HaloAUTAC
2G-HaloAUTAC (Compound tt44) is a Autophagy-targeting chimera (2G-HaloAUTAC) that improves the activity of AUTACs by replacing the L-Cysteine (L-Cys) linker with other structures. 2G-HaloAUTAC exhibits degradation activity against EGFP-HaloTag protein through an Autophagic mechanism.
For research use only. We do not sell to patients.
- CAS No.: 2241668-58-4
- Formula: C31H43ClFN7O6
- Molecular Weight:664.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
2G-HaloAUTAC (1 μM) shows a significant gene knockdown effect in HeLa cells that stably expressed EGFP-HT[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2241668-58-4
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Molecular Weight 664.17
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Formula C31H43ClFN7O6
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SMILES
O=C1N=C(NC2=C1N=C(N2CC3=CC=C(C=C3)F)C4=CN(CCOCCOCCOCCOCCOCCCCCCCl)N=C4)N
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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