2241668-58-4
2241668-58-4
Chemical Structure
2G-HaloAUTAC
- CAS No.: 2241668-58-4
- Formula:C31H43ClFN7O6
- Molecular Weight:664.17
InChIKey: CRDGQFMDDSPOAP-UHFFFAOYSA-N
SMILES: O=C1N=C(NC2=C1N=C(N2CC3=CC=C(C=C3)F)C4=CN(CCOCCOCCOCCOCCOCCCCCCCl)N=C4)N
Biological Activity: 2G-HaloAUTAC (Compound tt44) is a Autophagy-targeting chimera (2G-HaloAUTAC) that improves the activity of AUTACs by replacing the L-Cysteine (L-Cys) linker with other structures. 2G-HaloAUTAC exhibits degradation activity against EGFP-HaloTag protein through an Autophagic mechanism[1].
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2G-HaloAUTAC | 2G-HaloAUTAC (Compound tt44) is a Autophagy-targeting chimera (2G-HaloAUTAC) that improves the activity of AUTACs by replacing the L-Cysteine (L-Cys) linker with other structures. 2G-HaloAUTAC exhibits degradation activity against EGFP-HaloTag protein through an Autophagic mechanism. | |||||||||||||||||||||
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References
Keywords
