Kiss1 - KiSS-1 metastasis-suppressor Gene

Also Known as kisspeptin; metastatin

Species: Mus musculus

Gene Type: protein coding
Gene ID: 280287

Summary

Predicted to enable Kisspeptin Receptor binding activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; decidualization; and negative regulation of cell migration. Predicted to be located in several cellular components, including apical plasma membrane; extracellular space; and neuronal cell body. Predicted to be active in neuron projection. Is expressed in diencephalon and metanephros. Used to study hypogonadotropic hypogonadism 13 with or without anosmia. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 13 with or without anosmia. Orthologous to human KISS1 (KiSS-1 metastasis suppressor). [provided by Alliance of Genome Resources, Apr 2022]

Kiss1 Products (2)

mRNA Protein Name
NM_001412624.1 NP_001399553.1 metastasis-suppressor KiSS-1 precursor
NM_178260.4 NP_839991.2 metastasis-suppressor KiSS-1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12359743 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
12359743 MGI
acts upstream of or within decidualization IMP
IMP: Inferred from mutant phenotype
24830702 MGI
acts upstream of or within negative regulation of cell migration IPI
IPI: Inferred from physical interaction
12359743 MGI
acts upstream of or within negative regulation of cell population proliferation IPI
IPI: Inferred from physical interaction
12359743 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

metastasis-suppressor KiSS-1

  • 0610012C01Rik

  • Kiss1 metastasis-suppressor

  • kisspeptin-1

  • metastin

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-P0076 TAK-448 99.90% Phase 2
HY-P0076A TAK-448 acetate 99.79% Phase 2
HY-P2161 TAK-683 / Phase 1

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1196A Kisspeptin 234 TFA Antagonist 98.92% Unkown
HY-P1022 Kisspeptin-54(human) 99.39% Unkown
HY-P10489 Kisspeptin-14 human 99.70% Unkown
HY-P1197A Kisspeptin-10 (mouse, rat) TFA 99.57% Unkown
HY-P2161B TAK-683 acetate 99.91% Unkown
HY-P1197 Kisspeptin-10 (mouse, rat) 99.53% Unkown
HY-P1022A Kisspeptin-54(human) TFA 98.86% Unkown
HY-RS07316 KISS1R Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-P1196 Kisspeptin 234 Antagonist / Unkown
HY-P2161A TAK-683 TFA / Unkown
HY-P2191 KISS1-305 / Unkown
HY-RS07315 KISS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07317 Kiss1r Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07318 Kiss1r Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18527 Kiss1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25009 Kiss1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kiss1 NCBI NCBI:3814