Azidoethyl-SS-ethylamine
Based on 1 Customer Validation
Azidoethyl-SS-ethylamine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Azidoethyl-SS-ethylamine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 1807512-40-8
- 分子式: C4H10N4S2
- 分子量:178.28
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保管条件:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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Disulfide Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1807512-40-8
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性状 Liquid
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分子量 178.28
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分子式 C4H10N4S2
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Color Light yellow to yellow
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SMILES
NCCSSCCN=[N+]=[N-]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 250 mg/mL (1402.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.6092 mL | 28.0458 mL | 56.0915 mL | 140.2289 mL |
| 5 mM | 1.1218 mL | 5.6092 mL | 11.2183 mL | 28.0458 mL | |
| 10 mM | 0.5609 mL | 2.8046 mL | 5.6092 mL | 14.0229 mL | |
| 15 mM | 0.3739 mL | 1.8697 mL | 3.7394 mL | 9.3486 mL | |
| 20 mM | 0.2805 mL | 1.4023 mL | 2.8046 mL | 7.0114 mL | |
| 25 mM | 0.2244 mL | 1.1218 mL | 2.2437 mL | 5.6092 mL | |
| 30 mM | 0.1870 mL | 0.9349 mL | 1.8697 mL | 4.6743 mL | |
| 40 mM | 0.1402 mL | 0.7011 mL | 1.4023 mL | 3.5057 mL | |
| 50 mM | 0.1122 mL | 0.5609 mL | 1.1218 mL | 2.8046 mL | |
| 60 mM | 0.0935 mL | 0.4674 mL | 0.9349 mL | 2.3371 mL | |
| 80 mM | 0.0701 mL | 0.3506 mL | 0.7011 mL | 1.7529 mL | |
| 100 mM | 0.0561 mL | 0.2805 mL | 0.5609 mL | 1.4023 mL |
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