Aβ42 agonist-2
Based on 1 Customer Validation
Aβ42 agonist-2 (compound 7b) is a small molecule compound that can promote Aβ42 aggregation. Aβ42 agonist-2 can interact with Aβ42 oligomers and pentamers to promote nontoxic aggregate self-assembly and rapid fibril formation. Aβ42 agonist-2 prevents Aβ42-induced cytotoxicity in HT22 hippocampal neuronal cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.92%
- CAS 番号: 6314-40-5
- 分子式: C15H11NOS
- 分子量:253.32
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Aβ42 aggregation[1]
化学情報
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CAS 番号 6314-40-5
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性状 Solid
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分子量 253.32
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分子式 C15H11NOS
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SMILES
O=C(C1=CC2=C(C=CC=C2)S1)NC3=CC=CC=C3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 125 mg/mL (493.45 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.9476 mL | 19.7379 mL | 39.4758 mL | 98.6894 mL |
| 5 mM | 0.7895 mL | 3.9476 mL | 7.8952 mL | 19.7379 mL | |
| 10 mM | 0.3948 mL | 1.9738 mL | 3.9476 mL | 9.8689 mL | |
| 15 mM | 0.2632 mL | 1.3159 mL | 2.6317 mL | 6.5793 mL | |
| 20 mM | 0.1974 mL | 0.9869 mL | 1.9738 mL | 4.9345 mL | |
| 25 mM | 0.1579 mL | 0.7895 mL | 1.5790 mL | 3.9476 mL | |
| 30 mM | 0.1316 mL | 0.6579 mL | 1.3159 mL | 3.2896 mL | |
| 40 mM | 0.0987 mL | 0.4934 mL | 0.9869 mL | 2.4672 mL | |
| 50 mM | 0.0790 mL | 0.3948 mL | 0.7895 mL | 1.9738 mL | |
| 60 mM | 0.0658 mL | 0.3290 mL | 0.6579 mL | 1.6448 mL | |
| 80 mM | 0.0493 mL | 0.2467 mL | 0.4934 mL | 1.2336 mL | |
| 100 mM | 0.0395 mL | 0.1974 mL | 0.3948 mL | 0.9869 mL |
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