Carbiphene
Carbiphene is a GABAA receptor allosteric modulator. Carbiphene inhibits [35S] TBPS binding and enhances [3H] muscimol binding on rat forebrain membranes, acting on specific GABAA receptor subsets. Carbiphene can be used in research related to schizophrenia.
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- CAS 番号: 15687-16-8
- 分子式: C28H34N2O2
- 分子量:430.59
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Carbiphene inhibits the binding of [35S]TBPS to rat whole forebrain membranes with an IC50 of 12 μM[1].
Carbiphene enhances the binding of [3H]MUS to rat whole forebrain membranes, with an EC50 of 34 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 15687-16-8
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分子量 430.59
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分子式 C28H34N2O2
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SMILES
O=C(N(C)CCN(C)CCC=1C=CC=CC1)C(OCC)(C=2C=CC=CC2)C=3C=CC=CC3
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Squires RF, et al. Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research. Neurochem Res. 2000;25(12):1587-1601. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Carbiphene 関連分類
HY-105567 関連分類
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