GMFB - glia maturation factor beta Gene

Also Known as GMF

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 2764

About GMFB

Cytogenetic location: 14q22.2 Genomic coordinates (GRCh38): 14:54,474,485-54,488,980 (from NCBI)

This gene has 10 transcripts (splice variants), 204 orthologues and 1 paralogue. Ubiquitous expression in brain (RPKM 45.0), colon (RPKM 21.0) and 24 other tissues.

Summary

Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within learning and locomotory behavior. [provided by Alliance of Genome Resources, Apr 2022]

GMFB Products (1)

mRNA Protein Name
NM_004124.3 NP_004115.1 glia maturation factor beta

GMFB Protein Structure

Cofilin_ADF

Cofilin_ADF: Cofilin/tropomyosin-type actin-binding protein (13 - 138)

  • 0
  • 100
  • 142 a.a.
Protein Preferred Names Protein Names

glia maturation factor beta

  • GMF-beta

Recombinant GMFB Proteins

製品番号 製品名 アクセッション番号 純度
HY-P7362 Glia maturation factor beta/GMFB Protein, Human P60983 (M1-H142) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P70387 Glia maturation factor beta/GMFB Protein, Human (His) P60983 (M1-H142) ≥ 95%, as determined by reducing SDS-PAGE.

GMFB 抗体

製品番号 製品名 アプリケーション 反応性
HY-P811284 GMF beta Antibody WB, ICC/IF Human, Mouse, Rat

関連疾患

Diseases Alias
Arthrogryposis Multiplex Congenita 2, Neurogenic Type

  • Arthrogryposis Multiplex Congenita, Neurogenic Type

  • Amcn

  • Arthrogryposis Multiplex Congenita Neurogenic Type

  • AMC2

  • Amc, Neurogenic Type

  • Neurogenic-Type Arthrogryposis Multiplex Congenita-2

  • Amc Neurogenic Type

  • Neurogenic Type Of Amc

  • Neurogenic Arthrogryposis Multiplex Congenita

  • Arthrogryposis Multiplex Congenita, Neurogenic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS05518 GMFB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17885 Gmfb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24354 Gmfb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Felis catus GMFB VGNC VGNC:80964
Macaca mulatta GMFB VGNC VGNC:108300
Canis familiaris GMFB VGNC VGNC:41288
Rattus norvegicus GMFB RGD RGD:70910
Bos taurus GMFB VGNC VGNC:29434
Mus musculus GMFB MGD MGI:1927133
Others GMFB NCBI