Lta4h - leukotriene A4 hydrolase Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 299732

Summary

Enables leukotriene-A4 hydrolase activity. Involved in several processes, including leukotriene metabolic process; response to zinc ion; and type I pneumocyte differentiation. Located in cytoplasm and nucleus. Biomarker of adenocarcinoma; asthma; and squamous cell carcinoma. Orthologous to human LTA4H (Leukotriene A4 hydrolase). [provided by Alliance of Genome Resources, Apr 2022]

Lta4h Products (1)

mRNA Protein Name
NM_001030031.2 NP_001025202.1 leukotriene A-4 hydrolase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence 参考文献 由来
enables leukotriene-A4 hydrolase activity IDA
IDA: Inferred from direct assay
3995081 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in leukotriene metabolic process IDA
IDA: Inferred from direct assay
3995081 RGD
involved in response to peptide hormone IEP
IEP: Inferred from expression pattern
10601658 RGD
involved in response to zinc ion IEP
IEP: Inferred from expression pattern
17985342 RGD
involved in type I pneumocyte differentiation IEP
IEP: Inferred from expression pattern
15805137 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

leukotriene A-4 hydrolase

  • LTA-4 hydrolase

  • tripeptide aminopeptidase LTA4H

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
製品番号 製品名 製品効果
純度 Phase
HY-10825 DG051 Inhibitor 99.86% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-137298 LYS006 Inhibitor 98.41% Unkown
HY-103226 SC-57461A Inhibitor 99.93% Unkown
HY-162710 LTA4H-IN-5 Inhibitor / Unkown
HY-10828 SC-57461 Inhibitor / Unkown
HY-137298A LYS006 hydrochloride Inhibitor / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Lta4h NCBI NCBI:4048
Mus musculus Lta4h NCBI NCBI:16993