GNE-140
GNE-140 (Compound 28) is an external racemic mixture of (R)-GNE-140 (HY-100742A) and (S)-GNE-140 (HY-100742B). GNE-140 is an effective lactate dehydrogenase (LDH) inhibitor, with the IC50 values for LDHA and LDHB being 9 nM and 30 nM respectively. GNE-140 can be used in cancer research.
For research use only. We do not sell to patients.
- Purity: 98.43%
- CAS No.: 1809794-70-4
- Formula: C25H23ClN2O3S2
- Molecular Weight:499.04
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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LDHA 9 nM (IC50) |
LDHB 30 nM (IC50) |
Chemical Information
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CAS No. 1809794-70-4
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Appearance Solid
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Molecular Weight 499.04
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Formula C25H23ClN2O3S2
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Color Light yellow to brown
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SMILES
O=C1NC(C2=CC=C(N3CCOCC3)C=C2)(CC(O)=C1SC4=C(Cl)C=CC=C4)C5=CSC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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