1809794-70-4
1809794-70-4
Chemical Structure
GNE-140
- CAS No.: 1809794-70-4
- Formula:C25H23ClN2O3S2
- Molecular Weight:499.04
IUPAC Name: 3-((2-chlorophenyl)thio)-4-hydroxy-6-(4-morpholinophenyl)-6-(thiophen-3-yl)-5,6-dihydropyridin-2(1H)-one
InChIKey: SUFXXEIVBZJOAP-UHFFFAOYSA-N
SMILES: O=C1NC(C2=CC=C(N3CCOCC3)C=C2)(CC(O)=C1SC4=C(Cl)C=CC=C4)C5=CSC=C5
Biological Activity: GNE-140 (Compound 28) is an external racemic mixture of (R)-GNE-140 (HY-100742A) and (S)-GNE-140 (HY-100742B). GNE-140 is an effective lactate dehydrogenase (LDH) inhibitor, with the IC50 values for LDHA and LDHB being 9 nM and 30 nM respectively. GNE-140 can be used in cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GNE-140 | 98.43% | GNE-140 (Compound 28) is an external racemic mixture of (R)-GNE-140 (HY-100742A) and (S)-GNE-140 (HY-100742B). GNE-140 is an effective lactate dehydrogenase (LDH) inhibitor, with the IC50 values for LDHA and LDHB being 9 nM and 30 nM respectively. GNE-140 can be used in cancer research. | ||||||||||||||||||||
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