IDO1-IN-13
IDO1-IN-13 (compound 27a) is a potent IDO1 inhibitor with an IC50 of 61.6 nM. IDO1-IN-13 has cellular IDO1 inhibition (HeLa EC50= 30 nM). IDO1-IN-13 decreases 51% of the kyn/trp ratio in SK-OV-3 xenograft tumor tissues.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C20H16BrN5O2S
- 분자량:470.34
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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IDO1 30 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Detroit 551 | CC50 |
>10 μM
Compound: 27a
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Cytotoxicity against human Detroit 551 cells assessed as reduction in cell viability after 72 hrs by MTS assay
Cytotoxicity against human Detroit 551 cells assessed as reduction in cell viability after 72 hrs by MTS assay
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[PMID: 34929581] |
Chemical Information
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분자량 470.34
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화학식 C20H16BrN5O2S
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SMILES
N#CC1=CC=C(C=C1)NC(NCC2=CSC(/C(NC3=CC=CC(Br)=C3)=N/O)=C2)=O
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선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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