Ikarisoside B
Ikarisoside B is a potent and selective Organic cation transporter 1 (OCT1) inhibitor with an IC50 of 11.18 μM. Ikarisoside B shows selectivity over OCT2 (IC50 = 56.54 μM). Ikarisoside B can be used for the research of metabolic disease.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 113558-10-4
- 화학식: C32H38O15
- 분자량:662.64
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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OCT1 11.18 μM (IC50) |
OCT2 56.54 μM (IC50) |
Ikarisoside B (up to 250 μM; 12 h) shows no cytotoxicity in HEK-EV, HEK-OCT1 and HEK-OCT2 cells up to 250 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HEK-EV, HEK-OCT1 and HEK-OCT2 cells
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Concentration:up to 250 μM
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Incubation Time:12 h
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Result:Exhibited no cytotoxicity in HEK-EV, HEK-OCT1 and HEK-OCT2 cells up to 250 μM, with cell viability > 90%.
Showed 100% cell survival rate in HEK-EV, HEK-OCT1 and HEK-OCT2 cells.
Chemical Information
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CAS No. 113558-10-4
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분자량 662.64
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화학식 C32H38O15
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SMILES
O(C1=C(OC=2C(C1=O)=C(O)C=C(O)C2CC=C(C)C)C3=CC=C(O)C=C3)[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@H](O)[C@@H](O)[C@H](C)O4
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)