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Cat. No.: HY-130971

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Mal-PEG4-bis-PEG3-DBCO

Mal-PEG4-bis-PEG3-DBCO is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Mal-PEG4-bis-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

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CAS No.: 2882973-10-4
화학식: C₈₁H₁₀₅N₉O₂₂
분자량:1556.75

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (274 KB)

Mal-PEG4-bis-PEG3-DBCO Chemical Structure

CAS No.: 2882973-10-4

사이즈

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재고

수량

Amount: USD 0.00

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Use of MCE Products

One-stop CDMO Service

One-Stop Platform：From Independent R&D to Pilot-Scale Production

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Mal-PEG4-bis-PEG3-DBCO is a cleavable 7 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)^[1]. Mal-PEG4-bis-PEG3-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

IC₅₀ & Target

Cleavable Linker

All ADC Linkers Isoforms :

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2882973-10-4
분자량 1556.75
화학식 C₈₁H₁₀₅N₉O₂₂
SMILES

O=C(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)NC(COCCC(NCCOCCOCCOCCNC(CCC(N2C(C=CC=C3)=C3C#CC(C=CC=C4)=C4C2)=O)=O)=O)COCCC(NCCOCCOCCOCCNC(CCC(N5C(C=CC=C6)=C6C#CC(C=CC=C7)=C7C5)=O)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Amount: USD 0.00

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References

상품명:
Cat. No.:
수량:
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Mal-PEG4-bis-PEG3-DBCO

All ADC Linkers Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

Mal-PEG4-bis-PEG3-DBCO Related Classifications

HY-130971 Related Classifications