PDHK1-IN-2
PDHK1-IN-2 (Compound 24) is an ATP-competitive dual inhibitor of pyruvate dehydrogenase kinases 1/2 (PDHK1/2), with an IC50 of 0.007 μM for PDHK1 and an IC50 of 0.015 μM for PDHK2. PDHK1-IN-2 can regulate immune cell metabolism and correct mitochondrial dysfunction, and is expected to be used in the research of autoimmune diseases, inflammatory diseases, cancers, and other conditions.
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- CAS No.: 2870691-38-4
- 화학식: C25H33FN6O2
- 분자량:468.57
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2870691-38-4
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분자량 468.57
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화학식 C25H33FN6O2
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SMILES
CCNC1=CC(F)=CC(C2(CC)N3CCC[C@@H](NC(C4CC5(CN(C#N)C5)C4)=O)C3)=C1NC2=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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