Tau-aggregation-IN-4
Tau-aggregation-IN-4 is a Tau-aggregation inhibitor (EC50 = 2.99 μM). Tau-aggregation-IN-4 can be used for the study of neurodegenerative disorders such as Alzheimer’s and Pick’s diseases.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 화학식: C23H21N5O2
- 분자량:399.45
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Tau-aggregation-IN-4 (Compound 1a) (10-30 μM, 24 h) scavenges tau aggregates at both 10 μM and 30 μM concentrations (EC50 = 2.99 μM) in SH-SY5Y cells, with an average maximum clearance of 62%, and is non-cytotoxic[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 399.45
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화학식 C23H21N5O2
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SMILES
O=C(C1=CNC2=C1C=CC(NC(CCC3(CCC#C)N=N3)=O)=C2)NC4=CC=CC=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tau-aggregation-IN-4 Related Classifications
HY-178927 Related Classifications
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