Sideritoflavone
Sideritoflavone is a flavonoid. Sideritoflavone can be isolated from Baccharis densiflora. Sideritoflavone is toxic to JIMT-1 breast cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 70360-12-2
- Formula: C18H16O8
- Molecular Weight:360.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16-F10 | IC50 |
5.6 μM
Compound: 10
|
Anti-inflammatory activity in LPS-stimulated mouse B16-F10 cells assessed as reduction in TNFalpha production measured for 12 hrs by ELISA method
Anti-inflammatory activity in LPS-stimulated mouse B16-F10 cells assessed as reduction in TNFalpha production measured for 12 hrs by ELISA method
|
[PMID: 37683361] |
| RBL-2H3 | IC50 |
>500 μM
Compound: 9
|
Antihistaminic activity in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced beta-hexosaminidase release preincubated for 10 mins before DNP-BSA challenge
Antihistaminic activity in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced beta-hexosaminidase release preincubated for 10 mins before DNP-BSA challenge
|
[PMID: 14510616] |
| THP-1 | IC50 |
12.4 μM
Compound: 10
|
Anti-inflammatory activity in LPS-stimulated human THP-1 cells assessed as reduction of TNFalpha measured for 12 hrs by ELISA method
Anti-inflammatory activity in LPS-stimulated human THP-1 cells assessed as reduction of TNFalpha measured for 12 hrs by ELISA method
|
[PMID: 37683361] |
Chemical Information
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CAS No. 70360-12-2
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Molecular Weight 360.31
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Formula C18H16O8
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SMILES
O=C1C=C(C2=CC=C(O)C(O)=C2)OC3=C(OC)C(OC)=C(OC)C(O)=C13
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Synonyms
Sideritiflavone
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)