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Cat. No.: HY-180452

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HAT-IN-10

HAT-IN-10 (Compound 12a) is an anti-human African trypanosomiasis (HAT) agent, with an EC₅₀ value of 0.23 μM for T. brucei. HAT-IN-10 can be used for research on HAT.

For research use only. We do not sell to patients.

CAS No.: 2998560-77-1
Formula: C₂₅H₂₈N₆
Molecular Weight:412.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

HAT-IN-10 Chemical Structure

CAS No.: 2998560-77-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

HAT-IN-10 (Compound 12a) is an anti-human African trypanosomiasis (HAT) agent, with an EC₅₀ value of 0.23 μM for T. brucei. HAT-IN-10 can be used for research on HAT^[1].

Chemical Information

CAS No. 2998560-77-1
Molecular Weight 412.53
Formula C₂₅H₂₈N₆
SMILES

CN1C=C(C2=CC=C3C(C4=C(N3CCNC(C)C)C=CC(C5=CN(C)N=C5)=C4)=C2)C=N1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Singh B, et al. Chemical Optimization of CBL0137 for Human African Trypanosomiasis Lead Drug Discovery. J Med Chem. 2023 Feb 9;66(3):1972-1989. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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