Dusp4 - dual specificity phosphatase 4 Gene

Also Known as Mkp2; Mkp-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 60587

Summary

Enables MAP kinase tyrosine/serine/threonine Phosphatase activity and protein tyrosine/threonine Phosphatase activity. Involved in protein dephosphorylation. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human DUSP4 (dual specificity Phosphatase 4). [provided by Alliance of Genome Resources, Apr 2022]

Dusp4 Products (1)

mRNA Protein Name
NM_022199.2 NP_071535.2 dual specificity protein phosphatase 4

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables MAP kinase tyrosine/serine/threonine phosphatase activity IDA
IDA: Inferred from direct assay
7782322 RGD
enables protein tyrosine/threonine phosphatase activity IDA
IDA: Inferred from direct assay
12435803 RGD
Biological Process GO Annotation Evidence References Source
involved in protein dephosphorylation IDA
IDA: Inferred from direct assay
12435803 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dual specificity protein phosphatase 4

  • MAP kinase phosphatase 2

  • mitogen-activated protein kinase phosphatase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-202699 SHOC2-RAS PPI-IN-1 Inhibitor 99.50% Unkown
HY-164350 KRAS inhibitor-27 Inhibitor 98.27% Unkown
HY-RS26515 Dusp4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04065 DUSP4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20012 Dusp4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dusp4 NCBI NCBI:1846