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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
CSPGs
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "CSPGs" in MCE Product Catalog:
2
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Áreas de investigación:
Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury .
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1 Cited Publications
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Chst15-IN-1 is a potent reversible covalent Chst15 inhibitor. Chst15-IN-1 effectively inhibits chondroitin sulfate-E (CS-E) sulfation levels and other closely related glycosaminoglycans (GAG) sulfotransferases. Chst15-IN-1, as a selective sulfotransferase inhibitor, can diminish the inhibitory effects of chondroitin sulfate proteoglycans (CSPGs), and can be used for the stimulation of neuronal repair .
Synonyms: C286
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KCL-286 (C286) is an orally active and brain-penetrant retinoic acid receptor (RAR) β2 agonist (EC50 = 1.9 nM). KCL-286 targets RARβ2 with good selectivity over RAR α (EC50 = 26 nM) and RAR γ (EC50 = 11 nM). KCL-286 activates RARβ2 in the injured neurons. KCL-286 induces axonal regeneration of both spinal and sensory nerves through the inhibitory environment of the CNS, modulates neuroinflammation and extracellular matrix molecules. KCL-286 can modulate the expression of CSPGs by neuronal secretion of decorin which promotes myelination and aids axonal growth. KCL-286 can be studied in research for area such as spinal cord injury and traumatic nerve injury .
Referencia número: HY-P5982
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Áreas de investigación:
Referencia número: HY-RS26166
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Áreas de investigación:
Cspg4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cspg4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS03254
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CSPG4 Human Pre-designed siRNA Set A contains three designed siRNAs for CSPG4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS03255
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CSPG5 Human Pre-designed siRNA Set A contains three designed siRNAs for CSPG5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS19673
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Cspg4 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cspg4 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-P11838
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Referencia número: HY-RS18656
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Cspg5 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Cspg5 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Referencia número: HY-RS25142
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Áreas de investigación:
Cspg5 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cspg5 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
