9024-13-9
9024-13-9
Chemical Structure
Chondroitinase ABC
Synonym(s): ChABC
- CAS No.: 9024-13-9
- Formula:N/A
- Molecular Weight:N/A
InChIKey: VNWKTOKETHGBQD-UHFFFAOYSA-N
SMILES: [Chondroitinase ABC]
Biological Activity: Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury[1][2].
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Chondroitinase ABC | Chondroitinase ABC (ChABC) is an enzyme that degrades glycosaminoglycan side-chains of chondroitin sulfate (CS-GAG) from the chondroitin sulfate proteoglycan (CSPG) core protein. Chondroitinase ABC facilitates reinnervation by degrading CS-GAGs around motoneurons. Chondroitinase ABC has the potential for the research of spinal injury. | |||||||||||||||||||||
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Chondroitinase ABC I | Chondroitinase ABC I is a hydrolase with high catalytic efficiency, high specificity, mild action conditions, etc., and can be used in the pharmaceutical industry, industrial production, food manufacturing, aquaculture and other industries. | |||||||||||||||||||||
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Chondroitinase ABC II | Chondroitinase ABC II is a hydrolase. Enzymes have high catalytic efficiency, high specificity, and mild operating conditions. It can be applied in industries such as pharmaceuticals, industrial production, food manufacturing, and aquaculture. | |||||||||||||||||||||
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References
- [1]. Mahajan R, et al. Chondroitinase ABC Enzyme: A Potential Treatment Option for Spinal Cord Injury. Int J Appl Basic Med Res. 2018 Oct-Dec;8(4):203.
- [2]. Takiguchi M, et al. Chondroitinase ABC Administration Facilitates Serotonergic Innervation of Motoneurons in Rats With Complete Spinal Cord Transection. Front Integr Neurosci. 2022 Jun 30;16:881632. [Content Brief]
