6 Results for "

sirtuin+6

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "sirtuin+6" in MCE Product Catalog:

31
31 Publications Verification
Cat. No.: HY-107454
CAS No.: 887686-02-4
Purity:  98.63%
OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects .
17
17 Cited Publications
Cat. No.: HY-115453
CAS No.: 358721-70-7
Purity:  98.88%
Target:  

Sirtuin Autophagy

Research Areas:  

Cancer

UBCS039 is the first synthetic, specific Sirtuin 6 (SIRT6) activator, inducing autophagy in human tumor cells, with an EC50 of 38 μM .
1
1 Cited Publications
Cat. No.: HY-P80322
Synonyms: SIR2L6, SIRT6, NAD-dependent protein deacylase sirtuin-6, NAD-dependent protein deacetylase sirtuin-6, Protein mono-ADP-ribosyltransferase sirtuin-6, Regulatory protein SIR2 homolog 6, SIR2-like protein 6, hSIRT6

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P, FC

Reactivity:  

Human, Mouse

Cat. No.: HY-169159
CAS No.: 2867630-96-2
Target:  

Sirtuin

Research Areas:  

Metabolic Disease

SIRT6 activator 2 (compound 31) is a sirtuin 6 activator with anti-lipid accumulation properties. SIRT6 activator 2 significantly downregulates LXR, SREBP-1c, and their target genes associated with lipogenesis, and can be used for research related to lipid metabolism-related diseases .
Cat. No.: HY-P85522
Synonyms: 2810449N18Rik; AI043036; Mono ADP ribosyltransferase sirtuin 6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; Regulatory protein SIR2 homolog; SIR2 like 6; SIR2 like protein 6; Sir2 related protein type 6; SIR2-like protein 6; SIR2

Host:  

Mouse

Application:  

WB, ICC/IF, IP

Reactivity:  

Human, Mouse, Rat, Monkey

Cat. No.: HY-107454R
CAS No.: 887686-02-4
OSS_128167 (Standard) is the analytical standard of OSS_128167 (HY-107454). This product is intended for research and analytical applications. OSS_128167 is a potent selective sirtuin 6 (SIRT6) inhibitor with IC50s of 89 μM, 1578 μM and 751 μM for SIRT6, SIRT1 and SIRT2, respectively. OSS_128167 has anti-HBV activity that inhibits HBV transcription and replication. OSS_128167 has anti-cancer, anti-inflammation and anti-viral effects .