Decarbamoylmitomycin C
Decarbamoylmitomycin C, an analog of Mitomycin C (MC), is an DNA-alkylating agent. Decarbamoylmitomycin C (DMC) activates p53-independent ataxia telangiectasia and rad3 related protein (ATR) chromatin eviction.
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- CAS. Nr.: 26909-37-5
- Formel: C14H17N3O4
- Molecular Weight:291.30
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 26909-37-5
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Molecular Weight 291.30
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Formel C14H17N3O4
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SMILES
CO[C@]12N(C[C@@]3([H])[C@]2([H])N3)C4=C(C(C(N)=C(C4=O)C)=O)[C@H]1CO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Maggie Zheng, et al. Synthesis of Mitomycin C and decarbamoylmitomycin C N6 deoxyadenosine-adducts. Bioorg Chem. 2019 Nov:92:103280. [Content Brief]
[2]. Gu Xiao, et al. Decarbamoyl mitomycin C (DMC) activates p53-independent ataxia telangiectasia and rad3 related protein (ATR) chromatin eviction. Cell Cycle. 2015;14(5):744-54. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Decarbamoylmitomycin C Related Classifications
HY-167635 Related Classifications
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