FGFR1OP2 - FGFR1 oncogene partner 2 Gene

Also Known as WIT3.0; HSPC123-like

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 26127

About FGFR1OP2

Cytogenetic location: 12p11.23 Genomic coordinates (GRCh38): 12:26,938,470-26,966,648 (from NCBI)

This gene has 6 transcripts (splice variants), 220 orthologues and 1 paralogue. Ubiquitous expression in ovary (RPKM 23.0), adrenal (RPKM 22.0) and 25 other tissues.

Summary

Predicted to enable identical protein binding activity. Predicted to be involved in response to wounding. Predicted to act upstream of or within wound healing. Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

FGFR1OP2 Products (3)

mRNA Protein Name
NM_001171887.2 NP_001165358.1 FGFR1 oncogene partner 2 isoform 2
NM_001171888.2 NP_001165359.1 FGFR1 oncogene partner 2 isoform 3
NM_015633.3 NP_056448.1 FGFR1 oncogene partner 2 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FGFR1OP2 Protein Structure

SIKE

SIKE: SIKE family (1 - 134)

SIKE

SIKE: SIKE family (166 - 223)

  • 0
  • 100
  • 200
  • 253 a.a.
Protein Preferred Names Protein Names

FGFR1 oncogene partner 2

  • fibroblast growth factor receptor 1 oncogene partner 2

Related Diseases

Diseases Alias
Myeloid And Lymphoid Neoplasms Associated With Fgfr1 Abnormalities
Lymphoblastic Lymphoma

  • Lymphoma, Lymphoblastic

  • Lymphoma Lymphoblastic

  • Precursor Cell Lymphoblastic Lymphoma

  • Precursor Cell Lymphoblastic Leukemia Lymphoma
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS04914 FGFR1OP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FGFR1OP2 VGNC VGNC:28986
Canis familiaris FGFR1OP2 VGNC VGNC:40858
Mus musculus FGFR1OP2 MGD MGI:1914779
Rattus norvegicus FGFR1OP2 RGD RGD:1303233
Felis catus FGFR1OP2 VGNC VGNC:97437
Macaca mulatta FGFR1OP2 VGNC VGNC:72551
Others FGFR1OP2 NCBI