St3gal4 - ST3 beta-galactoside alpha-2,3-sialyltransferase 4 Gene

Also Known as siat4c; SIAT4-C; ST3GalIV

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 363040

Summary

Enables monosialoganglioside Sialyltransferase activity. Predicted to be involved in several processes, including cellular protein modification process; lipid glycosylation; and positive regulation of leukocyte tethering or rolling. Predicted to be located in Golgi cisterna membrane. Predicted to be integral component of membrane. Orthologous to human ST3GAL4 (ST3 beta-galactoside alpha-2,3-sialyltransferase 4). [provided by Alliance of Genome Resources, Apr 2022]

St3gal4 Products (5)

mRNA Protein Name
NM_001393863.1 NP_001380792.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 1
NM_001393864.1 NP_001380793.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 1
NM_001393865.1 NP_001380794.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 2 precursor
NM_001393866.1 NP_001380795.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 2 precursor
NM_203337.3 NP_976082.1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3- sialyltransferase IDA
IDA: Inferred from direct assay
2262006 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
8694795 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

  • N-acetyllactosaminide alpha-2,3-sialyltransferase

  • alpha 2,3-sialyltransferase IV

  • alpha-2,3-sialyltransferase ST3Gal IV

  • beta-galactoside alpha-2,3-sialyltransferase 4

  • gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase

  • gal-beta-1,4-GalNAc-alpha-2,3-sialyl

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS13849 ST3GAL4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18209 St3gal4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24686 St3gal4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens St3gal4 NCBI NCBI:6484