Slc25a37 - solute carrier family 25, member 37 Gene

Also Known as Mfrn; Mscp; Mfrn1; frascati; mitoferrin; 1700020E22Rik; 4930513O14Rik; 4930526G11Rik; C330015G08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 67712

Summary

Enables ferrous iron transmembrane transporter activity. Involved in iron import into the mitochondrion and positive regulation of Hemoglobin biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including central nervous system; immune system; liver; retina nuclear layer; and yolk sac. Orthologous to human SLC25A37 (solute carrier family 25 member 37). [provided by Alliance of Genome Resources, Apr 2022]

Slc25a37 Products (1)

mRNA Protein Name
NM_026331.3 NP_080607.2 mitoferrin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables ferrous iron transmembrane transporter activity EXP
EXP: Inferred from Experiment
16511496 MGI
enables iron ion transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
16511496 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
19805291 MGI
Biological Process GO Annotation Evidence Verweise Source
involved in iron import into the mitochondrion IMP
IMP: Inferred from mutant phenotype
16511496 MGI
involved in positive regulation of hemoglobin biosynthetic process IMP
IMP: Inferred from mutant phenotype
19805291 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
16511496 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
19805291 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitoferrin-1

  • mitochondrial iron transporter 1

  • mitochondrial solute carrier protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-121936 Yohimbic acid Inhibitor 99.86% Unkown
HY-RS13119 SLC25A37 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22075 Slc25a37 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28593 Slc25a37 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc25a37 NCBI NCBI:51312