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NMDA receptor antagonist 11

NMDA receptor antagonist 11 is a NMDA receptor antagonist with an IC₅₀ of 65 μM. NMDA receptor antagonist 11 inhibits glycine action at the NMDA receptor glycine site. NMDA receptor antagonist 11 can be used for research on neurological diseases.

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CAS. Nr.: 26727-26-4
Formel: C₆H₁₂N₂O₃
Molecular Weight:160.17

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NMDA receptor antagonist 11 Chemical Structure

CAS. Nr.: 26727-26-4

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

NMDA Receptor

65 μM (IC₅₀)

Alle iGluR Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
Oocyte	IC₅₀	65 μM Compound: 1	Activity at rat NR1/NR2A receptor expressed in Xenopus oocytes assessed as inhibition of glycine-induced electrophysiological response Activity at rat NR1/NR2A receptor expressed in Xenopus oocytes assessed as inhibition of glycine-induced electrophysiological response	[PMID: 19394821]

In Vitro

NMDA receptor antagonist 11 (Compound 1) exhibits an IC₅₀ of 65 μM against NMDA receptor glycine site^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 26727-26-4
Molecular Weight 160.17
Formel C₆H₁₂N₂O₃
SMILES

O=C(CNC(CCCN)=O)O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Nguyen KT, et al. 3-(aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitor from the chemical universe database GDB. Bioorg Med Chem Lett. 2009;19(14):3832-3835. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass

Konzentration

Volumen

Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
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- IC50 & Target
- In Vitro
Chemical Information
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