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Art. -Nr.: HY-183052

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RIPK3-IN-7

RIPK3-IN-7 is a RIPK3 inhibitor that suppresses the RIPK3-mediated necroptosis pathway. RIPK3-IN-7 can be used for research on necroptosis and inflammation-related diseases.

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CAS. Nr.: 3116772-57-4
Formel: C₂₄H₂₅N₃O₂S₂
Molecular Weight:451.60

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

RIPK3-IN-7 Chemical Structure

CAS. Nr.: 3116772-57-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
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Biologische Aktivität

Beschreibung

RIPK3-IN-7 is a RIPK3 inhibitor that suppresses the RIPK3-mediated necroptosis pathway. RIPK3-IN-7 can be used for research on necroptosis and inflammation-related diseases^[1].

Alle RIP kinase Isoform-spezifische Produkte anzeigen :

In Vitro

RIPK3-IN-7 (LK-18) (20 μM) inhibits RIPK3-mediated necrosis in L929 cells and HT29 cells, with an EC₅₀ of 1.2 μM, has a high selectivity ratio (CC₅₀/EC₅₀) of 44.3, and does not induce Caspase-3 activation at 20 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3116772-57-4
Molecular Weight 451.60
Formel C₂₄H₂₅N₃O₂S₂
SMILES

O=S(=O)(C=1C=CC2=NC=CC(NC=3C=CC=4SC(=NC4C3)C5CCCC5)=C2C1)C(C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Xu YC, et al. 2-Substituted azole cell necrosis pathway inhibitor and preparation method and application thereof. CN121471209A. 2025-08-05.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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RIPK3-IN-7

Alle RIP kinase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

RIPK3-IN-7 Related Classifications

HY-183052 Related Classifications