ELOVL2 - ELOVL fatty acid elongase 2 Gene

Also Known as SSC2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54898

About ELOVL2

Cytogenetic location: 6p24.2 Genomic coordinates (GRCh38): 6:10,980,759-11,044,305 (from NCBI)

This gene has 1 transcript (splice variant), 156 orthologues and 6 paralogues. Biased expression in placenta (RPKM 12.7), liver (RPKM 10.4) and 6 other tissues.

Summary

Enables fatty acid elongase activity. Involved in fatty acid elongation, polyunsaturated fatty acid and very long-chain fatty acid biosynthetic process. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

ELOVL2 Products (1)

mRNA Protein Name
NM_017770.4 NP_060240.3 elongation of very long chain fatty acids protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables fatty acid elongase activity EXP
EXP: Inferred from Experiment
10970790 GOA
enables fatty acid elongase activity IDA
IDA: Inferred from direct assay
12371743 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
20937905 GOA
Biological Process GO Annotation Evidence References Source
involved in fatty acid elongation, polyunsaturated fatty acid IDA
IDA: Inferred from direct assay
12371743 GOA
involved in very long-chain fatty acid biosynthetic process IDA
IDA: Inferred from direct assay
12371743 GOA
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
20937905 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ELOVL2 Protein Structure

ELO

ELO: GNS1/SUR4 family (31 - 264)

  • 0
  • 100
  • 200
  • 296 a.a.
Protein Preferred Names Protein Names

elongation of very long chain fatty acids protein 2

  • 3-keto acyl-CoA synthase ELOVL2

Related Diseases

Diseases Alias
Retinitis Pigmentosa 37

  • RP37

  • Retinitis Pigmentosa-37

  • Retinitis Pigmentosa, Type 37
Inguinal Hernia

  • Hernia Inguinal

  • Hernia, Inguinal

  • Inguinal Hernias

  • Bubonocele

  • Indirect Inguinal Hernia

  • Direct Inguinal Hernia

  • Oblique Inguinal Hernia

  • Scrotal Hernia

  • Ih - [Inguinal Hernia]
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS21122 Elovl2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS04322 ELOVL2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27641 Elovl2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ELOVL2 RGD RGD:1308605
Bos taurus ELOVL2 VGNC VGNC:28448
Macaca mulatta ELOVL2 VGNC VGNC:72045
Mus musculus ELOVL2 MGD MGI:1858960
Canis familiaris ELOVL2 VGNC VGNC:40320
Felis catus ELOVL2 VGNC VGNC:61823
Others ELOVL2 NCBI