Glucosylceramide synthase (GCS)

Definition:

Glucosylceramide synthase (GCS) is an enzyme inherent to ceramide metabolism. The enzyme catalyzes the transfer of glucose to ceramide, the first committed step in glycolipid biosynthesis.

References:

[1]. Bleicher RJ, Cabot MC. Glucosylceramide synthase and apoptosis. Biochim Biophys Acta. 2002 Dec 30;1585(2-3):172-8. [Content Brief]

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