Zinc transporter 10
Definition:
References:
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[1]. Yitong Zhao, et al. Differential Targeting of SLC30A10/ZnT10 Heterodimers to Endolysosomal Compartments Modulates EGF-Induced MEK/ERK1/2 Activity. Traffic. 2016 Mar;17(3):267-88. [Content Brief]
[2]. Marialuisa Quadri, et al. Mutations in SLC30A10 cause parkinsonism and dystonia with hypermanganesemia, polycythemia, and chronic liver disease. Am J Hum Genet. 2012 Mar 9;90(3):467-77. [Content Brief]
[3]. Nikolay Patrushev, et al. Angiotensin II requires zinc and downregulation of the zinc transporters ZnT3 and ZnT10 to induce senescence of vascular smooth muscle cells. PLoS One. 2012;7(3):e33211. [Content Brief]
[4]. Helen J Bosomworth, et al. Efflux function, tissue-specific expression and intracellular trafficking of the Zn transporter ZnT10 indicate roles in adult Zn homeostasis. Metallomics. 2012 Aug;4(8):771-9. [Content Brief]
[5]. Yukina Nishito, et al. Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter. J Biol Chem. 2016 Jul 8;291(28):14773-87. [Content Brief]
[6]. Karin Tuschl, et al. Syndrome of hepatic cirrhosis, dystonia, polycythemia, and hypermanganesemia caused by mutations in SLC30A10, a manganese transporter in man. Am J Hum Genet. 2012 Mar 9;90(3):457-66. [Content Brief]
[7]. Charles E Zogzas, et al. Structural Elements in the Transmembrane and Cytoplasmic Domains of the Metal Transporter SLC30A10 Are Required for Its Manganese Efflux Activity. J Biol Chem. 2016 Jul 29;291(31):15940-57. [Content Brief]
[8]. Dinorah Leyva-Illades, et al. SLC30A10 is a cell surface-localized manganese efflux transporter, and parkinsonism-causing mutations block its intracellular trafficking and efflux activity. J Neurosci. 2014 Oct 15;34(42):14079-95. [Content Brief]
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