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LRRC10 - leucine rich repeat containing 10 Gene

Also Known as HRLRRP; LRRC10A

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 376132

About LRRC10

Cytogenetic location: 12q15 Genomic coordinates (GRCh38): 12:69,608,564-69,610,907 (from NCBI)

This gene has 1 transcript (splice variant), 110 orthologues and 31 paralogues.

Summary

Predicted to enable actin binding activity. Predicted to be involved in cardiac muscle cell development. Predicted to be located in myofibril. Predicted to be active in Cytoskeleton and sarcomere. [provided by Alliance of Genome Resources, Apr 2022]

LRRC10 Products (1)

mRNA	Protein	Name
NM_201550.4	NP_963844.2	leucine-rich repeat-containing protein 10

LRRC10 Protein Structure

LRR_4

LRR_1

0
100
200
277 a.a.

Protein Preferred Names	Protein Names
leucine-rich repeat-containing protein 10	heart-restricted leucine-rich repeat protein

Related Diseases

Diseases	Alias
Intellectual Developmental Disorder With Cardiac Arrhythmia	Gnb5-Related Intellectual Disability-Cardiac Arrhythmia Syndrome IDDCA Intellectual Developmental Disorder, With Cardiac Arrhythmia
Anomalous Left Coronary Artery From The Pulmonary Artery	Bland White Garland Syndrome Alcapa Bland-White-Garland Syndrome White-Garland Syndrome
Brugada Syndrome	Sudden Unexpected Nocturnal Death Syndrome Sudden Unexplained Nocturnal Death Syndrome Bangungut Brugada Type Idiopathic Ventricular Fibrillation Pokkuri Death Syndrome Sunds Idiopathic Ventricular Fibrillation, Brugada Type Sudden Unexplained Death Dream Disease Right Bundle Branch Block, St Segment Elevation, And Sudden Death Syndrome Sudden Unexplained Death Syndrome Suds Sunds - [Sudden Unexplained Nocturnal Death Syndrome]
Dilated Cardiomyopathy	Familial Dilated Cardiomyopathy Primary Dilated Cardiomyopathy Idiopathic Dilated Cardiomyopathy Congestive Cardiomyopathy Idiopathic Dilation Cardiomyopathy Primary Familial Dilated Cardiomyopathy Cardiomyopathy, Dilated DCM Cardiomyopathy, Familial Dilated Dilated Cardiomyopathy, Familial Hypokinetic Dilated Cardiomyopathy, Familial Familial Idiopathic Cardiomyopathy Fdc Cardiomyopathy, Familial Idiopathic Idiopathic Cardiomegaly Dilated Congestive Cardiomyopathy Chronic Dilated Cardiomyopathy Ccm - [Congestive Cardiomyopathy] Cocm - [Congestive Cardiomyopathy] Dcm - [Dilated Cardiomyopathy] Dilated-Hypokinetic Cardiomyopathy Congestive Idiopathic Cardiomyopathy Primary Idiopathic Dilated Cardiomyopathy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07807	LRRC10 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	LRRC10	VGNC	VGNC:52796
Rattus norvegicus	LRRC10	RGD	RGD:1307358
Mus musculus	LRRC10	MGD	MGI:2448063
Canis familiaris	LRRC10	VGNC	VGNC:54525
Felis catus	LRRC10	VGNC	VGNC:63286
Others	LRRC10	NCBI