Ybx1 - Y box binding protein 1 Gene

Also Known as Yb1; Byb1; Cbfa; Dbpb; Ef1a; Msy1; Nsep1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 500538

Summary

Enables nucleic acid binding activity and p53 binding activity. Involved in several processes, including negative regulation of apoptotic process; negative regulation of Insulin Receptor signaling pathway; and regulation of transcription by RNA polymerase II. Located in several cellular components, including dendrite; neuronal cell body; and perinuclear region of cytoplasm. Part of messenger ribonucleoprotein complex. Biomarker of myocardial infarction. Orthologous to human YBX1 (Y-box binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Ybx1 Products (1)

mRNA Protein Name
NM_031563.3 NP_113751.3 Y-box-binding protein 1
Molecular Function GO Annotation Evidence References Source
enables RNA binding IDA
IDA: Inferred from direct assay
23159318 RGD
enables mRNA binding IPI
IPI: Inferred from physical interaction
16508950 RGD
enables p53 binding IMP
IMP: Inferred from mutant phenotype
16158057 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
23159318 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
16278212 RGD
enables single-stranded DNA binding IDA
IDA: Inferred from direct assay
17893273 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
16158057 RGD
involved in negative regulation of insulin receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
12554649 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12835324 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15615704 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
15615704 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
14559349 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
14559349 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
16002047 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
20596529 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Y-box-binding protein 1

  • CBF-A

  • CCAAT-binding transcription factor 1 subunit A

  • CCAAT-binding transcription factor I subunit A

  • DNA binding protein B

  • EFI-A

  • Y box transcription factor

  • YB-1

  • enhancer factor 1 alpha

  • enhancer factor 1 subunit A

  • enhancer factor I subunit A

  • nucle

Orthologs Information

Species Symbol Source ID
Homo sapiens Ybx1 NCBI NCBI:4904