Glucose oxidase
Based on 7 publication(s) in Google Scholar
Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation.
For research use only. We do not sell to patients.
- CAS No.: 9001-37-0
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Glucose oxidase
More- Adv Sci (Weinh). 2025 Sep 8:e08636. [Abstract]
- Biomaterials. 2022 Nov:290:121821. [Abstract]
- Mater Today Bio. 2025 Nov 1:35:102496. [Abstract]
- Mater Today Bio. 2025 Nov 13:35:102547. [Abstract]
- Mater Today Bio. 2025 Mar 24:32:101702. [Abstract]
- Int J Nanomedicine. 2025 Dec 6:20:14613-14628. [Abstract]
- J Electroanal Chem. 2023 Sep 16, 117808.
Customer Validation & Images
-
Bio/Physico-chemical Assay
-
Bio/Physico-chemical Assay
-
Bio/Physico-chemical Assay
-
Bio/Physico-chemical Assay
-
Bio/Physico-chemical Assay
All Endogenous Metabolite Isoforms
More
Biological Activity
|
Microbial Metabolite |
Glucose oxidase is a subset of oxidoreductase enzymes that catalyzes the transfer of electrons from an oxidant to a reductant. Glucose oxidases use oxygen as an external electron acceptor that releases hydrogen peroxide (H2O2). Glucose oxidase has many applications in commercial processes, including improving the color and taste, increasing the persistence of food materials, removing the glucose from the dried egg, and eliminating the oxygen from different juices and beverages[4].
Product Information
Theoretical molecular weight: 160 kDa
pH effective range: 4.0-8.0, optimum pH 5.5
Optimum temperature: 30°C-45°C
Temperature stability: <50°C (pH 5.0, 15 min)
Isoelectric point: 4.2
No activator required, inhibitors are Ag+, Hg2+, Cu2+
Instructions
Soluble in water, or according to the specific experimental reference (e.g. 1.0 mg/mL in 50 mM sodium acetate buffer, pH 5.7)
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
1.1.3.4
≥300 U/mg protein
One unit is defined as the amount of enzyme that oxidize 1 μmol of glucose per min at pH 5.7 at 37°C
Chemical Information
-
CAS No. 9001-37-0
-
Appearance Solid
-
Color Light yellow to yellow
-
SMILES
[Glucose oxidase]
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (7)
-
Journal Impact Factor
-
Most Recent
-
Adv Sci (Weinh)
Self-Propelled Magnetic Micromotor-Functionalized DNA Tile System for Autonomous Capture of Circulating Tumor Cells in Clinical Diagnostics. [Abstract]2025 Sep 8:e08636. PMID: 40916920 -
Biomaterials
Biomimetic cell membrane-coated glucose/oxygen-exhausting nanoreactor for remodeling tumor microenvironment in targeted hypoxic tumor therapy. [Abstract]2022 Nov:290:121821. PMID: 36201949 -
Mater Today Bio
CD24-targeted cystine and glucose oxidase cascade catalytic nanosystem triggers disulfidptosis in neuroblastoma. [Abstract]2025 Nov 1:35:102496. PMID: 41281650 -
Mater Today Bio
SLC7A11-independent disulfidptosis induced by a two-pronged delivery strategy for bladder cancer chemotherapy and cisplatin-resistance reverse. [Abstract]2025 Nov 13:35:102547. PMID: 41322137
Glucose oxidase purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Nov 13:35:102547. [Abstract]
pH values due to the Gox (Glucose oxidase), Gox-Mn NPs, Cys-Gox-Mn NPs and M@Cys-Gox-Mn-catalyzed oxidation of glucose (1000 μg/mL).
Glucose oxidase purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Nov 13:35:102547. [Abstract]
Enzymatic activity of Gox (Glucose oxidase, 1 mg/mL) at different pH for indicated durations.
Glucose oxidase purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Nov 13:35:102547. [Abstract]
Enzymatic activity of Gox (Glucose oxidase, 1 mg/mL) in M@Cys-Gox-Mn NPs at different pH for indicated durations.
Glucose oxidase purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Nov 13:35:102547. [Abstract]
The glucose concentration in the T24 cells after treated by Gox (Glucose oxidase), Gox-Mn NPs, Cys-Gox-Mn NPs, and M@Cys-Gox-Mn NPs, respectively. Gox-equivalent dose: 0.2 μg/ml, 2 h incubation.
Glucose oxidase purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Nov 13:35:102547. [Abstract]
The ATP levels in the T24 cells after treated by Gox (Glucose oxidase), Gox-Mn NPs, Cys-Gox-Mn NPs, and M@Cys-Gox-Mn NPs, respectively. Gox-equivalent dose: 0.2 μg/ml, 2 h incubation.
Glucose oxidase purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Nov 13:35:102547. [Abstract]
The NAPDH levels in the T24 cells after treated by Gox (Glucose oxidase), Gox-Mn NPs, Cys-Gox-Mn NPs, and M@Cys-Gox-Mn NPs, respectively. Gox-equivalent dose: 0.2 μg/ml, 2 h incubation.
Glucose oxidase purchased from MedChemExpress. Usage Cited in: Mater Today Bio. 2025 Nov 13:35:102547. [Abstract]
Glucose oxidase: 0.2 μg/mL. Representative CLSM images of the cytoskeletal changes in T24/5637 cells. F-actin was stained with phalloidin. The cell nuclei were stained using Hoechst for 10 min.
-
Mater Today Bio
Reducing the availability of endogenous copper and glucose for cascade starvation therapy and chemodynamic therapy. [Abstract]2025 Mar 24:32:101702. PMID: 40230642 -
Int J Nanomedicine
2025 Dec 6:20:14613-14628. PMID: 41383278 -
Solvent & Solubility
H2O : 50 mg/mL (Need ultrasonic)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL; Clear solution; Need ultrasonic
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (418 KB)
- English - EN (418 KB)
- Français - FR (418 KB)
- Deutsch - DE (418 KB)
- Norwegian - NO (418 KB)
- Español - ES (418 KB)
- Swedish - SV (418 KB)
- Italian - IT (418 KB)
- Portuguese - PT (418 KB)
-
Handling Instructions (2659 KB)
References
[1]. Konishi T, et al. Safety evaluation of glucose oxidase from Penicillium chrysogenum [published correction appears in Regul Toxicol Pharmacol. 2013 Aug;66(3):300]. Regul Toxicol Pharmacol. 2013;66(1):13-23. [Content Brief]
[2]. Leskovac V, et al. Glucose oxidase from Aspergillus niger: the mechanism of action with molecular oxygen, quinones, and one-electron acceptors. Int J Biochem Cell Biol. 2005;37(4):731-750. [Content Brief]
[3]. Wang M, et al. Recent Advances in Glucose-Oxidase-Based Nanocomposites for Tumor Therapy. Small. 2019;15(51):e1903895. [Content Brief]
[4]. Khatami SH, et al. Glucose oxidase: Applications, sources, and recombinant production [published online ahead of print, 2021 Apr 11]. Biotechnol Appl Biochem. 2021;10.1002/bab.2165. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Powered by Bioz