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Cat. No.: HY-168607

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ALK5-IN-83

ALK5-IN-83 (compound 13b) is a ALK5 inhibitor with the IC₅₀ of 0.13 μM. ALK5-IN-83 inhibits TGF-β1-induced Smad2 phosphorylation and cell motility in A549 cells.

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Formule: C₂₀H₂₃N₇O₂S
Masse moléculaire:425.51

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

ALK5-IN-83 Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

ALK5-IN-83 (compound 13b) is a ALK5 inhibitor with the IC₅₀ of 0.13 μM. ALK5-IN-83 inhibits TGF-β1-induced Smad2 phosphorylation and cell motility in A549 cells^[1].

Voir tous les produits spécifiques à Isoform TGF-beta/Smad :

Smad1
Smad3

Chemical Information

Masse moléculaire 425.51
Formule C₂₀H₂₃N₇O₂S
SMILES

CCCCS(=O)(NCC1=NC(C2=CN3N=CN=C3C=C2)=C(N1)C4=CC=CC(C)=N4)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Ding SY, et al. Synthesis and biological evaluation of sulfonamide derivatives containing imidazole moiety as ALK5 inhibitors. Mol Divers. 2024 Aug 30. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
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ALK5-IN-83

Voir tous les produits spécifiques à Isoform TGF-beta/Smad

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

ALK5-IN-83 Related Classifications

HY-168607 Related Classifications