Antiproliferative agent-4
Antiproliferative agent-4 (compound 2y) has excellent anti-proliferative activity against certain cancer cell lines. Antiproliferative agent-4 reduces the mitochondrial membrane potential, and increases the apoptosis rate and the level of ROS on EC109. Antiproliferative agent-4 inhibits tumour growth in nude mice, with low toxicity.
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- Formule: C29H35ClO8
- Masse moléculaire:547.04
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
IC50: 0.13 ± 0.01 μM in EC109, 0.27 ± 0.02 μM in TE-1, 0.20 ± 0.01 μM in MGC-803, 0.35 ± 0.03 μM in MCF-7[1]
Antiproliferative agent-4 has inhibitory activity against cancer cell lines EC109, TE-1, MGC-803 and MCF-7 with IC50s of 0.13 ± 0.01 μM, 0.27 ± 0.02 μM, 0.20 ± 0.01 μM and 0.35 ± 0.03 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 547.04
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Formule C29H35ClO8
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SMILES
CC1(C)CCC[C@]2(COC(O)=O)C1C[C@@H](O)[C@]3(C4=O)C2[C@@H](O)C[C@@H](C4=C)[C@H]3OC(C5=CC=C(CCl)C=C5)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)