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Cat. No.: HY-184824

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CK2-IN-18

CK2-IN-18 is a protein kinase CK2 inhibitor with an IC₅₀ of > 30 μM against protein kinase CK2. CK2-IN-18 can be used in studies related to CK2-mediated signaling pathways, such as various cancers including lung cancer and breast cancer.

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CAS No.: 1417638-06-2
Formule: C₁₄H₁₅N₃O₄
Masse moléculaire:289.29

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

CK2-IN-18 Chemical Structure

CAS No.: 1417638-06-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

IC₅₀ & Target^[1]

CK2

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In Vitro

CK2-IN-18 (compound 19) does not potently inhibit recombinant human CK2, with an IC₅₀ greater than 30 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1417638-06-2
Masse moléculaire 289.29
Formule C₁₄H₁₅N₃O₄
SMILES

O=C1N=C(NC(CCC)=C1)NC2=CC=C(C(C(O)=O)=C2)O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Chekanov MO, et al. Design, synthesis and biological evaluation of 2-aminopyrimidinones and their 6-aza-analogs as a new class of CK2 inhibitors. Journal of enzyme inhibition and medicinal chemistry. 2014 Oct;29(5):639-46. [Content Brief]

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Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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CK2-IN-18

Voir tous les produits spécifiques à Isoform Casein Kinase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

CK2-IN-18 Related Classifications

HY-184824 Related Classifications