WDR3 - WD repeat domain 3 Gene

Also Known as DIP2; UTP12

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 10885

About WDR3

Cytogenetic location: 1p12 Genomic coordinates (GRCh38): 1:117,929,739-117,966,543 (from NCBI)

This gene has 4 transcripts (splice variants), 203 orthologues and 1 paralogue. Ubiquitous expression in testis (RPKM 13.4), appendix (RPKM 7.9) and 25 other tissues.

Summary

This gene encodes a nuclear protein containing 10 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, which usually include a trp-asp at the C-terminal end. Proteins belonging to the WD repeat family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, Apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]

WDR3 Products (1)

mRNA Protein Name
NM_006784.3 NP_006775.1 WD repeat-containing protein 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in ribosomal small subunit biogenesis IDA
IDA: Inferred from direct assay
34516797 GOA
Cellular Component GO Annotation Evidence Références Source
part of small-subunit processome IDA
IDA: Inferred from direct assay
34516797 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

WDR3 Protein Structure

WD40

WD40: WD domain, G-beta repeat (58 - 93)

WD40

WD40: WD domain, G-beta repeat (101 - 135)

WD40

WD40: WD domain, G-beta repeat (142 - 177)

WD40

WD40: WD domain, G-beta repeat (183 - 219)

WD40

WD40: WD domain, G-beta repeat (409 - 442)

WD40

WD40: WD domain, G-beta repeat (487 - 524)

WD40

WD40: WD domain, G-beta repeat (551 - 576)

WD40

WD40: WD domain, G-beta repeat (586 - 618)

WD40

WD40: WD domain, G-beta repeat (623 - 661)

WD40

WD40: WD domain, G-beta repeat (666 - 703)

Utp12

Utp12: Dip2/Utp12 Family (804 - 908)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 943 a.a.
Protein Preferred Names Protein Names

WD repeat-containing protein 3

  • dJ776P7.2 (WD repeat domain 3)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS15772 WDR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta WDR3 VGNC VGNC:78789
Mus musculus WDR3 MGD MGI:2443143
Canis familiaris WDR3 VGNC VGNC:48359
Rattus norvegicus WDR3 RGD RGD:1307480
Bos taurus WDR3 VGNC VGNC:36890
Felis catus WDR3 VGNC VGNC:67024
Others WDR3 NCBI