MOV10L1 - Mov10 like RISC complex RNA helicase 1 Gene

Also Known as CHAMP; SPGF73; DJ402G11.8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54456

About MOV10L1

Cytogenetic location: 22q13.33 Genomic coordinates (GRCh38): 22:50,090,006-50,161,687 (from NCBI)

This gene has 10 transcripts (splice variants), 148 orthologues, 10 paralogues and is associated with 1 phenotype. Restricted expression toward testis (RPKM 7.8).

Summary

This gene is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]

MOV10L1 Products (4)

mRNA Protein Name
NM_001164104.2 NP_001157576.1 RNA helicase Mov10l1 isoform 2
NM_001164105.2 NP_001157577.1 RNA helicase Mov10l1 isoform 3
NM_001164106.1 NP_001157578.1 RNA helicase Mov10l1 isoform 4
NM_018995.3 NP_061868.1 RNA helicase Mov10l1 isoform 1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Références Source
involved in germ cell development IEP
IEP: Inferred from expression pattern
11279525 GOA
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
11279525 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

MOV10L1 Protein Structure

AAA_11

AAA_11: AAA domain (745 - 831)

AAA_11

AAA_11: AAA domain (856 - 926)

AAA_12

AAA_12: AAA domain (935 - 1149)

  • 0
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  • 1000
  • 1211 a.a.
Protein Preferred Names Protein Names

RNA helicase Mov10l1

  • MOV10-like protein 1

Related Diseases

Diseases Alias
Spermatogenic Failure 73

  • SPGF73
Spermatogenic Failure

  • Azoospermia

  • Spgf

  • Spermatogenic Failure, Susceptibility To

  • Absent Sperm

  • Aspermatogenesis

  • Infertility Due To Azoospermia

  • Hypospermatogenesis

  • Azoospermatism
Male Infertility

  • Infertility, Male

  • Infertility Male

  • Male Sterility

  • Absolute Infertility
Infertility
Tracheomalacia

  • Congenital Tracheomalacia

  • Congenital Major Airway Collapse

  • Tracheomalacia, Congenital

  • Type 1 Tracheomalacia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS08604 MOV10L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MOV10L1 MGD MGI:1891384
Canis familiaris MOV10L1 VGNC VGNC:43328
Felis catus MOV10L1 VGNC VGNC:68303
Bos taurus MOV10L1 VGNC VGNC:31567
Macaca mulatta MOV10L1 VGNC VGNC:74912
Rattus norvegicus MOV10L1 RGD RGD:1304735
Others MOV10L1 NCBI