132858-26-5

YHV98-4 Chemical Structure
132858-26-5

Chemical Structure

YHV98-4

  • CAS No.: 132858-26-5
  • Formula:C16H13ClN2O2S
  • Molecular Weight:332.80

IUPAC Name: N-(4-chlorophenyl)-2-(3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazin-2-yl)acetamide

InChIKey: IYIITGYYTBUPTI-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(Cl)C=C1)CC2C(NC3=CC=CC=C3S2)=O

Biological Activity: YHV98-4 is a selective, blood-brain barrier-permeable Hv1 inhibitor with an IC50 of 0.7 μM. YHV98-4 reduces ROS production and restores the SHP-1-pAKT signaling pathway. YHV98-4 decreases the spread of hyperphosphorylated Tau protein. YHV98-4 alleviates inflammation and produces analgesic effects. YHV98-4 improves cognitive function in mouse models of Alzheimer's disease. YHV98-4 can be used in research related to inflammatory pain, neuropathic pain and Alzheimer's disease[1][2][3].

Cat. No. Product Name Purity Description Pricing
HY-W283930
YHV98-4 98.26% YHV98-4 is a selective, blood-brain barrier-permeable Hv1 inhibitor with an IC50 of 0.7 μM. YHV98-4 reduces ROS production and restores the SHP-1-pAKT signaling pathway. YHV98-4 decreases the spread of hyperphosphorylated Tau protein. YHV98-4 alleviates inflammation and produces analgesic effects. YHV98-4 improves cognitive function in mouse models of Alzheimer's disease. YHV98-4 can be used in research related to inflammatory pain, neuropathic pain and Alzheimer's disease.
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