169516-61-4
169516-61-4
Chemical Structure
2’-Deoxy-2’-fluoro-arabino-tubercidine
Synonym(s): T 70179
- CAS No.: 169516-61-4
- Formula:C11H13FN4O3
- Molecular Weight:268.24
IUPAC Name: (2R,3R,4S,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol
InChIKey: HEMKLVZUSCWYFZ-FBSDJGSXSA-N
SMILES: NC1=NC=NC2=C1C=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3F
Biological Activity: 2’-Deoxy-2’-fluoro-arabino-tubercidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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2’-Deoxy-2’-fluoro-arabino-tubercidine | 2’-Deoxy-2’-fluoro-arabino-tubercidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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References
