90035-08-8
Chemical Structure
Flocoumafen
Synonym(s): WL 108366
- CAS No.: 90035-08-8
- Formula:C33H25F3O4
- Molecular Weight:542.54
IUPAC Name: 4-hydroxy-3-(3-(4-((4-(trifluoromethyl)benzyl)oxy)phenyl)-1,2,3,4-tetrahydronaphthalen-1-yl)-2H-chromen-2-one
InChIKey: KKBGNYHHEIAGOH-UHFFFAOYSA-N
SMILES: O=C1C(C2CC(C3=CC=C(OCC4=CC=C(C(F)(F)F)C=C4)C=C3)CC5=C2C=CC=C5)=C(O)C6=CC=CC=C6O1
Biological Activity: Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Flocoumafen | 99.35% | Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects. | ||||||||||||||||||||
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Flocoumafen (Standard) | ≥98% | Flocoumafen (Standard) is the analytical standard of Flocoumafen. This product is intended for research and analytical applications. Flocoumafen (WL 108366) is an orally active vitamin K epoxide reductase inhibitor and a multi-target ligand, which includes prostaglandin F synthase, serum albumin, glucocorticoid receptor 2, and MMP-9. Flocoumafen is a second-generation anticoagulant rodenticide (ARs) with a half-life of 177.4 hours and has deadly anticoagulant effects. | ||||||||||||||||||||
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References
- [1]. Nadia Coronado-Posada, et al. In Silico Analysis to Identify Molecular Targets for Chemicals of Concern: The Case Study of Flocoumafen, an Anticoagulant Pesticide. Environ Toxicol Chem. 2021 Jul;40(7):2034-2043. [Content Brief]
- [2]. Sébastien Lefebvre, et al. Poisoning by Anticoagulant Rodenticides in Humans and Animals: Causes and Consequences.
- [3]. Huckle KR, et al. Elimination and accumulation of the rodenticide flocoumafen in rats following repeated oral administration. Xenobiotica. 1988 Dec;18(12):1465-79. [Content Brief]
