PM20D1 - peptidase M20 domain containing 1 Gene

Also Known as Cps1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 148811

About PM20D1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:205,828,025-205,850,132 (from NCBI)

This gene has 4 transcripts (splice variants), 215 orthologues and 3 paralogues. Biased expression in pancreas (RPKM 10.8), urinary bladder (RPKM 2.6) and 3 other tissues.

Summary

Enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides. Involved in several processes, including amide biosynthetic process; cellular amide catabolic process; and negative regulation of neuron death. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

PM20D1 Products (1)

mRNA Protein Name
NM_152491.5 NP_689704.4 N-fatty-acyl-amino acid synthase/hydrolase PM20D1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Verweise Source
enables hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides EXP
EXP: Inferred from Experiment
27374330 GOA
Biological Process GO Annotation Evidence Verweise Source
involved in amide biosynthetic process IDA
IDA: Inferred from direct assay
27374330 GOA
involved in amide catabolic process IDA
IDA: Inferred from direct assay
27374330 GOA
involved in amino acid metabolic process IDA
IDA: Inferred from direct assay
27374330 GOA
involved in cellular lipid metabolic process IDA
IDA: Inferred from direct assay
27374330 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PM20D1 Protein Structure

Peptidase_M20

Peptidase_M20: Peptidase family M20/M25/M40 (121 - 488)

M20_dimer

M20_dimer: Peptidase dimerisation domain (240 - 383)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 502 a.a.
Protein Preferred Names Protein Names

N-fatty-acyl-amino acid synthase/hydrolase PM20D1

  • peptidase M20 domain-containing protein 1

Related Diseases

Diseases Alias
Transient Arthritis
Norwegian Scabies

  • Crusted Scabies

  • Seven Year Itch
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-139006 N-Oleoyl glutamine Inhibitor / Unkown
HY-RS10757 PM20D1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus PM20D1 RGD RGD:1564063
Mus musculus PM20D1 MGD MGI:2442939
Felis catus PM20D1 VGNC VGNC:64252
Bos taurus PM20D1 VGNC VGNC:33066
Canis familiaris PM20D1 VGNC VGNC:44727
Macaca mulatta PM20D1 VGNC VGNC:76118
Others PM20D1 NCBI