ARHGAP30 - Rho GTPase activating protein 30 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 257106

About ARHGAP30

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:161,046,946-161,069,891 (from NCBI)

This gene has 7 transcripts (splice variants), 126 orthologues and 3 paralogues. Broad expression in lymph node (RPKM 43.4), spleen (RPKM 39.2) and 17 other tissues.

Summary

Predicted to enable GTPase activator activity. Predicted to be involved in small GTPase mediated signal transduction. Located in intracellular membrane-bounded organelle. [provided by Alliance of Genome Resources, Apr 2022]

ARHGAP30 Products (4)

mRNA Protein Name
NM_001025598.2 NP_001020769.1 rho GTPase-activating protein 30 isoform 1
NM_001287600.2 NP_001274529.1 rho GTPase-activating protein 30 isoform 3
NM_001287602.2 NP_001274531.1 rho GTPase-activating protein 30 isoform 4
NM_181720.3 NP_859071.2 rho GTPase-activating protein 30 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Verweise Source
enables protein binding IPI
IPI: Inferred from physical interaction
21565175 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ARHGAP30 Protein Structure

RhoGAP

RhoGAP: RhoGAP domain (34 - 182)

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  • 1101 a.a.
Protein Preferred Names Protein Names

rho GTPase-activating protein 30

  • rho-type GTPase-activating protein 30

ARHGAP30 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Verweise
Intra
ARHGAP30 Q7Z6I6 RHOU Homo sapiens Q7L0Q8
Anti Tag CoIP
21565175
Intra
ARHGAP30 Q7Z6I6 RHOU Homo sapiens Q7L0Q8
Y2H
21565175
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS00929 ARHGAP30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22057 Arhgap30 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28575 Arhgap30 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ARHGAP30 RGD RGD:1561419
Bos taurus ARHGAP30 VGNC VGNC:26088
Canis familiaris ARHGAP30 VGNC VGNC:38057
Felis catus ARHGAP30 VGNC VGNC:59887
Macaca mulatta ARHGAP30 VGNC VGNC:99847
Mus musculus ARHGAP30 MGD MGI:2684948
Others ARHGAP30 NCBI