ASRGL1 - asparaginase and isoaspartyl peptidase 1 Gene

Also Known as ALP; ALP1; CRASH

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 80150

About ASRGL1

Cytogenetic location: 11q12.3 Genomic coordinates (GRCh38): 11:62,337,448-62,401,431 (from NCBI)

This gene has 11 transcripts (splice variants), 211 orthologues, 2 paralogues and is associated with 1 phenotype. Biased expression in testis (RPKM 38.7), kidney (RPKM 13.5) and 10 other tissues.

Summary

Enables asparaginase activity and beta-aspartyl-peptidase activity. Involved in asparagine catabolic process via L-aspartate. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ASRGL1 Products (2)

mRNA Protein Name
NM_001083926.2 NP_001077395.1 isoaspartyl peptidase/L-asparaginase
NM_025080.4 NP_079356.3 isoaspartyl peptidase/L-asparaginase

ASRGL1 Protein Structure

Asparaginase_2

Asparaginase_2: Asparaginase (4 - 292)

  • 0
  • 100
  • 200
  • 308 a.a.
Protein Preferred Names Protein Names

isoaspartyl peptidase/L-asparaginase

  • L-asparaginase

Related Diseases

Diseases Alias
Immunodeficiency 48

  • Combined Immunodeficiency Due To Zap70 Deficiency

  • IMD48

  • Selective T-Cell Defect

  • Stcd

  • Zeta-Associated-Protein 70 Deficiency

  • Severe Combined Immunodeficiency, Atypical

  • Immunodeficiency, Type 48

  • Zap70 Deficiency
Aspartylglucosaminuria

  • Aspartylglycosaminuria

  • Glycosylasparaginase Deficiency

  • Aspartylglucosaminidase Deficiency

  • Aga Deficiency

  • AGU

  • Aspartylglucosamidase Deficiency

  • Glycoasparaginase

  • Aspartylglucosamidase Deficiency

  • Hyperammonemia, Type Iii
Corneal Dystrophy, Meesmann, 1

  • Meesmann Corneal Dystrophy

  • Mecd

  • Corneal Dystrophy, Meesmann Epithelial

  • Juvenile Hereditary Epithelial Dystrophy

  • Corneal Dystrophy, Juvenile Epithelial Of Meesmann

  • MECD1

  • Meesmann Corneal Dystrophy 1

  • Meesmann Corneal Epithelial Dystrophy

  • Meesmann Epithelial Corneal Dystrophy

  • Corneal Dystrophy, Juvenile Epithelial, Of Meesmann

  • Stocker-Holt Dystrophy

  • Meesman Dystrophy

  • Meesman'S Corneal Dystrophy

  • Juvenile Hereditary Epithelial Dystrophy Of Meesmann

  • Corneal Dystrophy, Meesmann 1

  • Juvenile Epithelial Corneal Dystrophy Of Meesmann

  • Mcd

  • Dystrophy, Corneal, Meesmann
Normal Pressure Hydrocephalus

  • Low Pressure Hydrocephalus

  • Hydrocephalus Normal Pressure

  • Hydrocephalus, Normal Pressure

  • Normal Pressure Hydrocephalus Nos

  • Nph - [Normal Pressure Hydrocephalus]

  • Normal Pressure Hydrocephaly
Retinal Degeneration

  • Degeneration Of Retina
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-RS01108 ASRGL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21095 Asrgl1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27613 Asrgl1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta ASRGL1 VGNC VGNC:70081
Bos taurus ASRGL1 VGNC VGNC:26223
Mus musculus ASRGL1 MGD MGI:1913764
Canis familiaris ASRGL1 VGNC VGNC:38192
Felis catus ASRGL1 VGNC VGNC:59980
Rattus norvegicus ASRGL1 RGD RGD:708526
Others ASRGL1 NCBI