RSK4-IN-2
RSK4-IN-2 (compound 16o) is a potent, orally active RSK4 inhibitor with an IC50 of 17 nM. RSK4-IN-2 suppresses esophageal squamous cell carcinoma (ESCC) cell growth and invasion, by inhibiting phosphorylation of RSK4 downstream targets. RSK4-IN-2 inhibits tumor growth and metastasis in ESCC mouse models. RSK4-IN-2 can be used for ESCC research.
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- CAS. Nr.: 3034203-03-4
- Formel: C17H16N8O
- Molecular Weight:348.36
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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RSK4 17 nM (IC50) |
Chemical Information
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CAS. Nr. 3034203-03-4
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Molecular Weight 348.36
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Formel C17H16N8O
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SMILES
O=C1N(C2=NC(NC3=CC=C4NN=NC4=C3)=NC=C2N=C1)C5CCCC5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)